Page 161 - Manual Antibioticoterapia Unimed Londrina

II - TRATAMENTO E PROFILAXIA DE INFECÇÕES EM ADULTOS

Peso Ajustado
Peso Real Peso Ideal (se IMC>30 ou mais de 20% de
excesso de peso)
Meropenem
Moxifloxacina
Oseltamivir
Polimixina B
Tigeciclina
Vancomicina

REFERÊNCIAS
BRUNETTE DD, Resuscitation of the Morbidly Obese Patient, Am J Emerg Med, 2004,
22(1):40-7. [PubMed 14724877]

CHEYMOL G, Effects of Obesity on Pharmacokinetics: Implications for Drug Therapy, Clin
Pharmacokinetics, 2000, 39(3):215-31.[PubMed 11020136]
DEPARTAMENTO de Atenção Básica. Obesidade / Ministério da Saúde, Secretaria de Aten-
ção à Saúde, Departamento de Atenção Básica. Brasília: Ministério da Saúde, 2006. 108 p.
Il. – (Cadernos de Atenção Básica, n. 12) (Série A. Normas e Manuais Técnicos).
DEVINE BJ. Gentamicin therapy. Drug Intell Clin Pharm. 1974; 8:650-5.
HANLEY MJ, ABERNETHY DR, GREENBLATT DJ. Effects of obesity on the pharmacoki-
netics of drugs in humans. Clin Pharmacokinet. 2010; 49:71-87.[PubMed 20067334]
ERSTAD BL. Dosing of medications in morbidly obese patients in the intensive care unit
setting. Intensive Care Med. 2004; 30:18-32. [PubMed 14625670]
KATHLEEN M. Rasmussen and ANN L. Yaktine, Editors. Weight Gain During Pregnancy:
Reexamining the Guidelines. Institute of Medicine; National Research Council. http://www.
nap.edu/catalog/12584.html
PAI MP, BEARDEN DT. Antimicrobial dosing considerations in obese adult patients. Phar-
macotherapy. 2007 Aug;27(8):1081-91. doi: 10.1592/phco.27.8.1081. PMID: 17655508.
ROBINSON JD, LUPKIEWICZ SM, PALENIK L, et al, Determination of Ideal Body Weight
for Drug Dosage Calculations, Am J Hosp Pharm, 1983, 40(6):1016-9.[PubMed 6869387]
The Sanford guide to antimicrobial therapy. Dallas, TX :Antimicrobial Therapy, Inc., 1995.

WURTZ R, ITOKAZU G, AND RODVOLD K, “Antimicrobial Dosing in Obese Patients,” Clin
Infect Dis, 1997, 25(1):112-8. [PubMed 9243045]

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